Schematic model of the organization of respiratory chain complexes into a respiratory string. The basic unit (lower left) consists of two copies of complex I (blue), one copy of complex III2 (red), and two copies of complex IV (yellow). Association of basic units into a string is mediated by complex IV, which interacts with a neighbouring complex IV through a dimeric interface found in the X-ray structure.
Ref: Dudkina et al., (2010) BBA-Bioenergetics In press corrected proof. doi:10.1016/j.bbabio.2009.12.013.
En este esquema se muestra como los complejos permiten la formación de fibras que recorren las crestas mitocondriales y ayudan a mantener su organización y funcionalidad.